| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Histone deacetylase 11 |
|---|
| Ligand | BDBM50105330 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1506763 (CHEMBL3598922) |
|---|
| Ki | 43±n/a nM |
|---|
| Citation |  Carrillo, AK; Guiguemde, WA; Guy, RK Evaluation of histone deacetylase inhibitors (HDACi) as therapeutic leads for human African trypanosomiasis (HAT). Bioorg Med Chem23:5151-5 (2015) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Histone deacetylase 11 |
|---|
| Name: | Histone deacetylase 11 |
|---|
| Synonyms: | HD11 | HDA11_HUMAN | HDAC11 | Human HDAC11 |
|---|
| Type: | Chromatin regulator; hydrolase; repressor |
|---|
| Mol. Mass.: | 39187.66 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q96DB2 |
|---|
| Residue: | 347 |
|---|
| Sequence: | MLHTTQLYQHVPETRWPIVYSPRYNITFMGLEKLHPFDAGKWGKVINFLKEEKLLSDSML
VEAREASEEDLLVVHTRRYLNELKWSFAVATITEIPPVIFLPNFLVQRKVLRPLRTQTGG
TIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDL
DAHQGNGHERDFMDDKRVYIMDVYNRHIYPGDRFAKQAIRRKVELEWGTEDDEYLDKVER
NIKKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVFRMVRGRRVPILMVT
SGGYQKRTARIIADSILNLFGLGLIGPESPSVSAQNSDTPLLPPAVP
|
|
|
|---|
| BDBM50105330 |
|---|
| n/a |
|---|
| Name | BDBM50105330 |
|---|
| Synonyms: | CHEMBL1851943 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H30N4O2 |
|---|
| Mol. Mass. | 358.4778 |
|---|
| SMILES | CCCCc1nc2cc(\C=C\C(=O)NO)ccc2n1CCN(CC)CC |
|---|
| Structure | 
|
|---|
Search and Browse
