| Reaction Details |
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 | Report a problem with these data |
| Target | Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma |
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| Ligand | BDBM50106928 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1508846 (CHEMBL3603395) |
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| IC50 | <100000±n/a nM |
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| Citation |  Raubo, P; Andrews, DM; McKelvie, JC; Robb, GR; Smith, JM; Swarbrick, ME; Waring, MJ Discovery of potent, selective small molecule inhibitors ofa-subtype of type III phosphatidylinositol-4-kinase (PI4KIIIa). Bioorg Med Chem Lett25:3189-93 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma |
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| Name: | Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma |
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| Synonyms: | KIAA0589 | PI51C_HUMAN | PIP5K1-gamma | PIP5K1C | PIP5KIgamma | Phosphatidylinositol 4-phosphate 5-kinase type I gamma | Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma | Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma | PtdIns(4)P-5-kinase 1 gamma |
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| Type: | PROTEIN |
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| Mol. Mass.: | 73241.99 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1508846 |
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| Residue: | 668 |
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| Sequence: | MELEVPDEAESAEAGAVPSEAAWAAESGAAAGLAQKKAAPTEVLSMTAQPGPGHGKKLGH
RGVDASGETTYKKTTSSTLKGAIQLGIGYTVGHLSSKPERDVLMQDFYVVESIFFPSEGS
NLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVT
SDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNN
ILPRVVKMHLKFDLKGSTYKRRASKKEKEKSFPTYKDLDFMQDMPEGLLLDADTFSALVK
TLQRDCLVLESFKIMDYSLLLGVHNIDQHERERQAQGAQSTSDEKRPVGQKALYSTAMES
IQGGAARGEAIESDDTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHDG
DTVSVHRPSFYAERFFKFMSNTVFRKNSSLKSSPSKKGRGGALLAVKPLGPTAAFSASQI
PSEREEAQYDLRGARSYPTLEDEGRPDLLPCTPPSFEEATTASIATTLSSTSLSIPERSP
SETSEQPRYRRRTQSSGQDGRPQEEPPAEEDLQQITVQVEPACSVEIVVPKEEDAGVEAS
PAGASAAVEVETASQASDEEGAPASQASDEEDAPATDIYFPTDERSWVYSPLHYSAQAPP
ASDGESDT
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| BDBM50106928 |
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| n/a |
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| Name | BDBM50106928 |
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| Synonyms: | CHEMBL3600765 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H8N4S |
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| Mol. Mass. | 228.273 |
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| SMILES | Nc1nc2ccc(cc2s1)-c1cnccn1 |
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| Structure | 
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