| Reaction Details |
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 | Report a problem with these data |
| Target | Vesicular acetylcholine transporter |
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| Ligand | BDBM50108979 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1507628 (CHEMBL3600039) |
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| Ki | 0.870000±n/a nM |
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| Citation |  Tu, Z; Zhang, X; Jin, H; Yue, X; Padakanti, PK; Yu, L; Liu, H; Flores, HP; Kaneshige, K; Parsons, SM; Perlmutter, JS Synthesis and biological characterization of a promising F-18 PET tracer for vesicular acetylcholine transporter. Bioorg Med Chem23:4699-709 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Vesicular acetylcholine transporter |
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| Name: | Vesicular acetylcholine transporter |
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| Synonyms: | SLC18A3 | Solute carrier family 18 member 3 | VACHT | VACHT_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 56900.67 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1507628 |
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| Residue: | 532 |
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| Sequence: | MESAEPAGQARAAATKLSEAVGAALQEPRRQRRLVLVIVCVALLLDNMLYMVIVPIVPDY
IAHMRGGGEGPTRTPEVWEPTLPLPTPANASAYTANTSASPTAAWPAGSALRPRYPTESE
DVKIGVLFASKAILQLLVNPLSGPFIDRMSYDVPLLIGLGVMFASTVLFAFAEDYATLFA
ARSLQGLGSAFADTSGIAMIADKYPEEPERSRALGVALAFISFGSLVAPPFGGILYEFAG
KRVPFLVLAAVSLFDALLLLAVAKPFSAAARARANLPVGTPIHRLMLDPYIAVVAGALTT
CNIPLAFLEPTIATWMKHTMAASEWEMGMAWLPAFVPHVLGVYLTVRLAARYPHLQWLYG
ALGLAVIGASSCIVPACRSFAPLVVSLCGLCFGIALVDTALLPTLAFLVDVRHVSVYGSV
YAIADISYSVAYALGPIVAGHIVHSLGFEQLSLGMGLANLLYAPVLLLLRNVGLLTRSRS
ERDVLLDEPPQGLYDAVRLRERPVSGQDGEPRSPPGPFDACEDDYNYYYTRS
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| BDBM50108979 |
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| n/a |
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| Name | BDBM50108979 |
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| Synonyms: | CHEMBL3597316 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H32FNO4 |
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| Mol. Mass. | 441.535 |
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| SMILES | O[C@@H]1Cc2ccccc2C[C@H]1N1CCC(CC1)C(=O)c1ccc(OCCOCCF)cc1 |r| |
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| Structure | 
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