| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 2 |
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| Ligand | BDBM10867 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1511555 (CHEMBL3607055) |
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| Ki | 75±n/a nM |
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| Citation |  Vullo, D; De Luca, V; Del Prete, S; Carginale, V; Scozzafava, A; Capasso, C; Supuran, CT Sulfonamide inhibition studies of theż-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis. Bioorg Med Chem Lett25:3550-5 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 2 |
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| Name: | Carbonic anhydrase 2 |
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| Synonyms: | CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II) |
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| Type: | Enzyme |
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| Mol. Mass.: | 29250.71 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P00918 |
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| Residue: | 260 |
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| Sequence: | MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL
NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL
VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP
RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM
VDNWRPAQPLKNRQIKASFK
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| BDBM10867 |
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| n/a |
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| Name | BDBM10867 |
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| Synonyms: | 4-amino-6-chlorobenzene-1,3-disulfonamide | CHEMBL266240 | aromatic/heteroaromatic sulfonamide 12 |
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| Type | Small organic molecule |
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| Emp. Form. | C6H8ClN3O4S2 |
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| Mol. Mass. | 285.728 |
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| SMILES | Nc1cc(Cl)c(cc1S(N)(=O)=O)S(N)(=O)=O |
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| Structure | 
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