| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 1 |
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| Ligand | BDBM50112768 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1513879 (CHEMBL3611444) |
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| Ki | 60±n/a nM |
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| Citation |  Ombouma, J; Vullo, D; Dumy, P; Supuran, CT; Winum, JY Carbonic Anhydrase Glycoinhibitors belonging to the Aminoxysulfonamide Series. ACS Med Chem Lett6:819-21 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 1 |
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| Name: | Carbonic anhydrase 1 |
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| Synonyms: | CA-I | CA1 | CAB | CAH1_HUMAN | Carbonate dehydratase I | Carbonic anhydrase | Carbonic anhydrase 1 (CA I) | Carbonic anhydrase 1 (CA-I) | Carbonic anhydrase 1 (Recombinant CA I) | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase B | Carbonic anhydrase I | Carbonic anhydrase I (CA I) | Carbonic anhydrase I (CA-I) | Carbonic anhydrase I (CAI) | Carbonic anhydrase I (hCA I) | Carbonic anhydrase isoenzyme I (hCA I) | hCA |
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| Type: | Enzyme |
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| Mol. Mass.: | 28873.37 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P00915 |
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| Residue: | 261 |
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| Sequence: | MASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEI
INVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELH
VAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNF
DPSTLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAV
PMQHNNRPTQPLKGRTVRASF
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| BDBM50112768 |
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| n/a |
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| Name | BDBM50112768 |
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| Synonyms: | CHEMBL3609440 |
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| Type | Small organic molecule |
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| Emp. Form. | C6H12N2O5S |
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| Mol. Mass. | 224.235 |
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| SMILES | C[C@@H]1OC(NS(=O)(=O)ON)C=C[C@H]1O |r,c:10| |
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| Structure | 
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