| Reaction Details |
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 | Report a problem with these data |
| Target | LIP1, secretory lipase (Family 3) |
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| Ligand | BDBM50112881 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1512202 (CHEMBL3611484) |
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| IC50 | >200000±n/a nM |
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| Citation |  Guo, S; Huang, W; Zhang, J; Wang, Y Novel inhibitor against Malassezia globosa LIP1 (SMG1), a potential anti-dandruff target. Bioorg Med Chem Lett25:3464-7 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| LIP1, secretory lipase (Family 3) |
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| Name: | LIP1, secretory lipase (Family 3) |
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| Synonyms: | LIP1, secretory lipase (Family 3) |
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| Type: | PROTEIN |
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| Mol. Mass.: | 33701.74 |
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| Organism: | Malassezia globosa (strain ATCC MYA-4612 / CBS 7966)(Dandruff-associated fungus) |
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| Description: | ChEMBL_109860 |
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| Residue: | 304 |
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| Sequence: | MLFSRFVLLAFGSVAAVSASSIYARGRGGSSTDQPVANPYNTKEISLAAGLVQQTYCDST
ENGLKIGDSELLYTMGEGYARQRVNIYHSPSLGIAVAIEGTNLFSLNSDLHDAKFWQEDP
NERYIQYYPKGTKLMHGFQQAYNDLMDDIFTAVKKYKKEKNEKRVTVIGHSLGAAMGLLC
AMDIELRMDGGLYKTYLFGLPRLGNPTFASFVDQKIGDKFHSIINGRDWVPTVPPRALGY
QHPSDYVWIYPGNSTSAKLYPGQENVHGILTVAREFNFDDHQGIYFHTQIGAVMGECPAQ
VGAH
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| BDBM50112881 |
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| n/a |
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| Name | BDBM50112881 |
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| Synonyms: | CHEMBL1569345 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H16N2O3S2 |
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| Mol. Mass. | 336.429 |
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| SMILES | O=C1N(CCSC(=S)N2CCOCC2)C(=O)c2ccccc12 |
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| Structure | 
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