| Reaction Details |
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 | Report a problem with these data |
| Target | C-C chemokine receptor type 9 |
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| Ligand | BDBM50113355 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1510356 (CHEMBL3607106) |
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| IC50 | 27±n/a nM |
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| Citation |  Zhang, J; Romero, J; Chan, A; Goss, J; Stucka, S; Cross, J; Chamberlain, B; Varoglu, M; Chandonnet, H; Ryan, D; Lippa, B Biarylsulfonamide CCR9 inhibitors for inflammatory bowel disease. Bioorg Med Chem Lett25:3661-4 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C-C chemokine receptor type 9 |
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| Name: | C-C chemokine receptor type 9 |
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| Synonyms: | CCR9 | CCR9_HUMAN | GPR28 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42023.90 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1510356 |
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| Residue: | 369 |
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| Sequence: | MTPTDFTSPIPNMADDYGSESTSSMEDYVNFNFTDFYCEKNNVRQFASHFLPPLYWLVFI
VGALGNSLVILVYWYCTRVKTMTDMFLLNLAIADLLFLVTLPFWAIAAADQWKFQTFMCK
VVNSMYKMNFYSCVLLIMCISVDRYIAIAQAMRAHTWREKRLLYSKMVCFTIWVLAAALC
IPEILYSQIKEESGIAICTMVYPSDESTKLKSAVLTLKVILGFFLPFVVMACCYTIIIHT
LIQAKKSSKHKALKVTITVLTVFVLSQFPYNCILLVQTIDAYAMFISNCAVSTNIDICFQ
VTQTIAFFHSCLNPVLYVFVGERFRRDLVKTLKNLGCISQAQWVSFTRREGSLKLSSMLL
ETTSGALSL
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| BDBM50113355 |
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| n/a |
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| Name | BDBM50113355 |
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| Synonyms: | CHEMBL3604490 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H23ClN4O3S |
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| Mol. Mass. | 446.95 |
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| SMILES | CNc1ncc(O)c(n1)-c1cc(Cl)ccc1NS(=O)(=O)c1ccc(cc1)C(C)(C)C |
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| Structure | 
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