| Reaction Details |
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 | Report a problem with these data |
| Target | Sialic acid-binding Ig-like lectin 7 |
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| Ligand | BDBM50114355 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1511186 (CHEMBL3607813) |
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| IC50 | 1642000±n/a nM |
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| Citation |  Prescher, H; Gütgemann, S; Frank, M; Kuhfeldt, E; Watzl, C; Brossmer, R Synthesis and biological evaluation of 9-N-oxamyl sialosides as Siglec-7 ligands. Bioorg Med Chem23:5915-21 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sialic acid-binding Ig-like lectin 7 |
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| Name: | Sialic acid-binding Ig-like lectin 7 |
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| Synonyms: | AIRM-1 | AIRM1 | Adhesion inhibitory receptor molecule 1 | CD_antigen=CD328 | CDw328 | D-siglec | QA79 membrane protein | SIGL7_HUMAN | SIGLEC7 | Sialic acid-binding Ig-like lectin 7 | Siglec-7 | p75 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 51147.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_109858 |
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| Residue: | 467 |
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| Sequence: | MLLLLLLPLLWGRERVEGQKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDP
VHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGR
YFFRMEKGNIKWNYKYDQLSVNVTALTHRPNILIPGTLESGCFQNLTCSVPWACEQGTPP
MISWMGTSVSPLHPSTTRSSVLTLIPQPQHHGTSLTCQVTLPGAGVTTNRTIQLNVSYPP
QNLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQP
SNPLVLELQVHLGDEGEFTCRAQNSLGSQHVSLNLSLQQEYTGKMRPVSGVLLGAVGGAG
ATALVFLSFCVIFIVVRSCRKKSARPAADVGDIGMKDANTIRGSASQGNLTESWADDNPR
HHGLAAHSSGEEREIQYAPLSFHKGEPQDLSGQEATNNEYSEIKIPK
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| BDBM50114355 |
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| n/a |
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| Name | BDBM50114355 |
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| Synonyms: | CHEMBL3604070 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H22N3NaO10 |
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| Mol. Mass. | 415.3283 |
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| SMILES | [Na+].[H][C@]1(O[C@@](C[C@H](O)[C@H]1NC(C)=O)(OC)C([O-])=O)[C@H](O)[C@H](O)CNC(=O)C(N)=O |r| |
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| Structure | 
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