| Reaction Details |
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 | Report a problem with these data |
| Target | L-lactate dehydrogenase A chain |
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| Ligand | BDBM50114406 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1513323 (CHEMBL3611227) |
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| IC50 | >200000±n/a nM |
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| Citation |  Rupiani, S; Buonfiglio, R; Manerba, M; Di Ianni, L; Vettraino, M; Giacomini, E; Masetti, M; Falchi, F; Di Stefano, G; Roberti, M; Recanatini, M Identification of N-acylhydrazone derivatives as novel lactate dehydrogenase A inhibitors. Eur J Med Chem101:63-70 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| L-lactate dehydrogenase A chain |
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| Name: | L-lactate dehydrogenase A chain |
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| Synonyms: | Cell proliferation-inducing gene 19 protein | L-lactate dehydrogenase A | L-lactate dehydrogenase A Chain | LDH muscle subunit | LDH-A | LDH-M | LDHA | LDHA_HUMAN | Lactate dehydrogenase A (LDHA) | Renal carcinoma antigen NY-REN-59 |
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| Type: | Protein |
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| Mol. Mass.: | 36694.85 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P00338::PDB Code: 4ajp |
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| Residue: | 332 |
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| Sequence: | MATLKDQLIYNLLKEEQTPQNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLKG
EMMDLQHGSLFLRTPKIVSGKDYNVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFI
IPNVVKYSPNCKLLIVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGV
HPLSCHGWVLGEHGDSSVPVWSGMNVAGVSLKTLHPDLGTDKDKEQWKEVHKQVVESAYE
VIKLKGYTSWAIGLSVADLAESIMKNLRRVHPVSTMIKGLYGIKDDVFLSVPCILGQNGI
SDLVKVTLTSEEEARLKKSADTLWGIQKELQF
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| BDBM50114406 |
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| n/a |
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| Name | BDBM50114406 |
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| Synonyms: | CHEMBL3609811 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H21N3O6 |
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| Mol. Mass. | 423.4186 |
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| SMILES | COc1cc(cc(OC)c1OC)C(=O)N\N=C\c1c[nH]c(c1)-c1cccc(c1)C(O)=O |
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| Structure | 
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