| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Monoacylglycerol lipase ABHD6 |
|---|
| Ligand | BDBM50118168 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1514730 (CHEMBL3614931) |
|---|
| IC50 | 73±n/a nM |
|---|
| Citation |  Patel, JZ; van Bruchem, J; Laitinen, T; Kaczor, AA; Navia-Paldanius, D; Parkkari, T; Savinainen, JR; Laitinen, JT; Nevalainen, TJ Revisiting 1,3,4-Oxadiazol-2-ones: Utilization in the Development of ABHD6 Inhibitors. Bioorg Med Chem23:6335-45 (2015) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Monoacylglycerol lipase ABHD6 |
|---|
| Name: | Monoacylglycerol lipase ABHD6 |
|---|
| Synonyms: | 2-arachidonoylglycerol hydrolase | ABHD6 | ABHD6_HUMAN | Abhydrolase domain-containing protein 6 | Monoacylglycerol lipase ABHD6 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 38341.83 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_105457 |
|---|
| Residue: | 337 |
|---|
| Sequence: | MDLDVVNMFVIAGGTLAIPILAFVASFLLWPSALIRIYYWYWRRTLGMQVRYVHHEDYQF
CYSFRGRPGHKPSILMLHGFSAHKDMWLSVVKFLPKNLHLVCVDMPGHEGTTRSSLDDLS
IDGQVKRIHQFVECLKLNKKPFHLVGTSMGGQVAGVYAAYYPSDVSSLCLVCPAGLQYST
DNQFVQRLKELQGSAAVEKIPLIPSTPEEMSEMLQLCSYVRFKVPQQILQGLVDVRIPHN
NFYRKLFLEIVSEKSRYSLHQNMDKIKVPTQIIWGKQDQVLDVSGADMLAKSIANCQVEL
LENCGHSVVMERPRKTAKLIIDFLASVHNTDNNKKLD
|
|
|
|---|
| BDBM50118168 |
|---|
| n/a |
|---|
| Name | BDBM50118168 |
|---|
| Synonyms: | CHEMBL3613162 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H13N3O3 |
|---|
| Mol. Mass. | 283.282 |
|---|
| SMILES | Nc1cccc(Cn2nc(Oc3ccccc3)oc2=O)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
