| Reaction Details |
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 | Report a problem with these data |
| Target | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase |
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| Ligand | BDBM50116357 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1511512 (CHEMBL3606937) |
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| Ki | 4.5±n/a nM |
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| Citation |  Evans, GB; Cameron, SA; Luxenburger, A; Guan, R; Suarez, J; Thomas, K; Schramm, VL; Tyler, PC Tight binding enantiomers of pre-clinical drug candidates. Bioorg Med Chem23:5326-33 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase |
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| Name: | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase |
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| Synonyms: | 5'-methylthioadenosine nucleosidase | ACN002_0164 | APZ14_11155 | AWH59_13765 | BN17_45831 | ERS150876_00075 | IY32_16590 | MTA/SAH nucleosidase | MTAN | S-adenosylhomocysteine nucleosidase | mtn | mtnN | pfs |
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| Type: | PROTEIN |
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| Mol. Mass.: | 24362.21 |
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| Organism: | Escherichia coli |
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| Description: | ChEMBL_109859 |
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| Residue: | 232 |
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| Sequence: | MKIGIIGAMEEEVTLLRDKIEKRQTISLGGCEIYTGQLNGTEVALLKSGIGKVAAALGAT
LLLEHCKPDVIINTGSAGGLAPTLKVGDIVVSDEARYHDADVTAFGYEYGQLPGCPAGFK
ADDKLIAAAEACIAELNLNAVRGLIVSGDAFINGSVGLAKIRHNFPQAIAVEMEATAIAH
VCHNFNVPFVVVRAISDVADQQSHLSFDEFLAVAAKQSSLMVESLVQKLAHG
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| BDBM50116357 |
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| n/a |
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| Name | BDBM50116357 |
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| Synonyms: | CHEMBL3604360 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H19N5OS |
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| Mol. Mass. | 293.388 |
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| SMILES | CSC[C@@H]1CN(Cc2c[nH]c3c(N)ncnc23)C[C@H]1O |r| |
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| Structure | 
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