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Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase
LigandBDBM22113
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1511512 (CHEMBL3606937)
Ki 0.048000±n/a nM
Citation Evans, GBCameron, SALuxenburger, AGuan, RSuarez, JThomas, KSchramm, VLTyler, PC Tight binding enantiomers of pre-clinical drug candidates. Bioorg Med Chem23:5326-33 (2015) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase
Name:5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase
Synonyms:5'-methylthioadenosine nucleosidase | ACN002_0164 | APZ14_11155 | AWH59_13765 | BN17_45831 | ERS150876_00075 | IY32_16590 | MTA/SAH nucleosidase | MTAN | S-adenosylhomocysteine nucleosidase | mtn | mtnN | pfs
Type:PROTEIN
Mol. Mass.:24362.21
Organism:Escherichia coli
Description:ChEMBL_109859
Residue:232
Sequence:
MKIGIIGAMEEEVTLLRDKIEKRQTISLGGCEIYTGQLNGTEVALLKSGIGKVAAALGAT
LLLEHCKPDVIINTGSAGGLAPTLKVGDIVVSDEARYHDADVTAFGYEYGQLPGCPAGFK
ADDKLIAAAEACIAELNLNAVRGLIVSGDAFINGSVGLAKIRHNFPQAIAVEMEATAIAH
VCHNFNVPFVVVRAISDVADQQSHLSFDEFLAVAAKQSSLMVESLVQKLAHG
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  Blast E-value cutoff:
BDBM22113
n/a
NameBDBM22113
Synonyms:(3R,4S)-1-({4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl}methyl)-4-[(methylsulfanyl)methyl]pyrrolidin-3-ol | (3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-[(methylsulfanyl)methyl]pyrrolidin-3-ol | (3R,4S)-1-[(9-Deazaadenin-9-yl)methyl]-3-hydroxy-4-methylthiomethylpyrrolidine, 7 | DADMe-ImmA-Me | MT-DADMe-ImmA
Typen/a
Emp. Form.C13H19N5OS
Mol. Mass.293.388
SMILESCSC[C@H]1CN(Cc2c[nH]c3c(N)ncnc23)C[C@@H]1O |r|
Structure
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