| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A3 |
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| Ligand | BDBM50116878 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1515686 (CHEMBL3616300) |
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| Ki | 16±n/a nM |
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| Citation |  Tosh, DK; Crane, S; Chen, Z; Paoletta, S; Gao, ZG; Gizewski, E; Auchampach, JA; Salvemini, D; Jacobson, KA Rigidified A3 Adenosine Receptor Agonists: 1-Deazaadenine Modification Maintains High in Vivo Efficacy. ACS Med Chem Lett6:804-8 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A3 |
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| Name: | Adenosine receptor A3 |
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| Synonyms: | A3AR | AA3R_MOUSE | Adenosine A3 receptor | Adora3 | Gpcr2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36460.91 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1515686 |
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| Residue: | 319 |
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| Sequence: | MEADNTTETDWLNITYITMEAAIGLCAVVGNMLVIWVVKLNPTLRTTTVYFIVSLALADI
AVGVLVIPLAIAVSLQVKMHFYACLFMSCVLLIFTHASIMSLLAIAVHRYLRVKLTVRYR
TVTTQRRIWLFLGLCWLVSFLVGLTPMFGWNRKATLASSQNSSTLLCHFRSVVSLDYMVF
FSFITWILVPLVVMCIIYLDIFYIIRNKLSQNLTGFRETRAFYGREFKTAKSLFLVLFLF
ALCWLPLSIINFVSYFDVKIPDVAMCLGILLSHANSMMNPIVYACKIKKFKETYFLILRA
VRLCQTSDSLDSNMEQTTE
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| BDBM50116878 |
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| n/a |
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| Name | BDBM50116878 |
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| Synonyms: | CHEMBL3612940 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H22ClN5O3S |
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| Mol. Mass. | 471.96 |
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| SMILES | [H][C@]12C[C@]1([C@@H](O)[C@@H](O)[C@@H]2n1cnc2c(NCC)cc(nc12)C#Cc1ccc(Cl)s1)C(=O)NC |r| |
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| Structure | 
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