| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Glucagon receptor |
|---|
| Ligand | BDBM50119555 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1518547 (CHEMBL3619086) |
|---|
| Ki | 15±n/a nM |
|---|
| Citation |  Sammons, MF; Lee, EC Recent progress in the development of small-molecule glucagon receptor antagonists. Bioorg Med Chem Lett25:4057-64 (2015) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Glucagon receptor |
|---|
| Name: | Glucagon receptor |
|---|
| Synonyms: | GCGR | GL-R | GLR_HUMAN | Glucagon Receptor (GCGR) | Glucagon receptor (GlucR) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 54026.92 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P47871 |
|---|
| Residue: | 477 |
|---|
| Sequence: | MPPCQPQRPLLLLLLLLACQPQVPSAQVMDFLFEKWKLYGDQCHHNLSLLPPPTELVCNR
TFDKYSCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPRGQPWRDASQ
CQMDGEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLHCTRNAIHANL
FASFVLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYGIVANYC
WLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFENVQCWTSNDN
MGFWWILRFPVFLAILINFFIFVRIVQLLVAKLRARQMHHTDYKFRLAKSTLTLIPLLGV
HEVVFAFVTDEHAQGTLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEVQSELRRRWHRWRL
GKVLWEERNTSNHRASSSPGHGPPSKELQFGRGGGSQDSSAETPLAGGLPRLAESPF
|
|
|
|---|
| BDBM50119555 |
|---|
| n/a |
|---|
| Name | BDBM50119555 |
|---|
| Synonyms: | CHEMBL3617571 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H26F3N5O3 |
|---|
| Mol. Mass. | 501.5008 |
|---|
| SMILES | CC(C)C[C@H](Nc1ccc(cn1)C(=O)NCCC(O)=O)c1cnc(nc1)-c1ccc(cc1)C(F)(F)F |r| |
|---|
| Structure | 
|
|---|
Search and Browse
