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TargetSerine racemase
LigandBDBM50119561
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1516972
Ki>10000000±n/a nM
Citation Dellafiora LMarchetti MSpyrakis FOrlandi VCampanini BCruciani GCozzini PMozzarelli A Expanding the chemical space of human serine racemase inhibitors. Bioorg Med Chem Lett 25:4297-303 (2015) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Serine racemase
Name:Serine racemase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:36565.80
Organism:Homo sapiens (Human)
Description:ChEMBL_1516972
Residue:340
Sequence:
MCAQYCISFADVEKAHINIRDSIHLTPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGA
LNAVRSLVPDALERKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQA
YGASIVYCEPSDESRENVAKRVTEETEGIMVHPNQEPAVIAGQGTIALEVLNQVPLVDAL
VVPVGGGGMLAGIAITVKALKPSVKVYAAEPSNADDCYQSKLKGKLMPNLYPPETIADGV
KSSIGLNTWPIIRDLVDDIFTVTEDEIKCATQLVWERMKLLIEPTAGVGVAAVLSQHFQT
VSPEVKNICIVLSGGNVDLTSSITWVKQAERPASYQSVSV
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50119561
n/a
NameBDBM50119561
Synonyms:CHEMBL3617725
TypeSmall organic molecule
Emp. Form.C10H15NO4
Mol. Mass.213.2304
SMILESOC(=O)CC1(CN2CCC1CC2)C(O)=O |THB:3:4:8.7:10.11,12:4:8.7:10.11,(0,2.93,;-1.3,2.21,;-2.57,2.97,;-1.32,.35,;.3,-.59,;2.12,-3.48,;-1.06,-4.26,;.27,-3.48,;.27,-1.94,;-1.06,-1.19,;-2.37,-1.94,;-2.37,-3.48,;1.9,.37,;3.19,-.37,;1.89,1.85,)|
Structure
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