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TargetCCR4-NOT transcription complex subunit 7
LigandBDBM50119763
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1518114 (CHEMBL3619397)
IC50 15100±n/a nM
Citation Jadhav, GPKaur, IMaryati, MAirhihen, BFischer, PMWinkler, GS Discovery, synthesis and biochemical profiling of purine-2,6-dione derivatives as inhibitors of the human poly(A)-selective ribonuclease Caf1. Bioorg Med Chem Lett25:4219-24 (2015) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
CCR4-NOT transcription complex subunit 7
Name:CCR4-NOT transcription complex subunit 7
Synonyms:BTG1-binding factor 1 | CAF-1 | CAF1 | CCR4-NOT transcription complex subunit 7 | CCR4-associated factor 1 | CNOT7 | CNOT7_HUMAN | Caf1a
Type:PROTEIN
Mol. Mass.:32730.66
Organism:Homo sapiens (Human)
Description:ChEMBL_109881
Residue:285
Sequence:
MPAATVDHSQRICEVWACNLDEEMKKIRQVIRKYNYVAMDTEFPGVVARPIGEFRSNADY
QYQLLRCNVDLLKIIQLGLTFMNEQGEYPPGTSTWQFNFKFNLTEDMYAQDSIELLTTSG
IQFKKHEEEGIETQYFAELLMTSGVVLCEGVKWLSFHSGYDFGYLIKILTNSNLPEEELD
FFEILRLFFPVIYDVKYLMKSCKNLKGGLQEVAEQLELERIGPQHQAGSDSLLTGMAFFK
MREMFFEDHIDDAKYCGHLYGLGSGSSYVQNGTGNAYEEEANKQS
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  Blast E-value cutoff:
BDBM50119763
n/a
NameBDBM50119763
Synonyms:CHEMBL3616529
TypeSmall organic molecule
Emp. Form.C14H13N3O2
Mol. Mass.255.2719
SMILESOc1cc2n(CCc3ccccc3)cnc2[nH]c1=O
Structure
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