| Reaction Details |
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 | Report a problem with these data |
| Target | Sphingosine 1-phosphate receptor 2 |
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| Ligand | BDBM50120514 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1518045 (CHEMBL3619046) |
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| IC50 | 690±n/a nM |
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| Citation |  Kusumi, K; Shinozaki, K; Yamaura, Y; Hashimoto, A; Kurata, H; Naganawa, A; Ueda, H; Otsuki, K; Matsushita, T; Sekiguchi, T; Kakuuchi, A; Seko, T Discovery of novel S1P2 antagonists. Part 2: Improving the profile of a series of 1,3-bis(aryloxy)benzene derivatives. Bioorg Med Chem Lett25:4387-92 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sphingosine 1-phosphate receptor 2 |
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| Name: | Sphingosine 1-phosphate receptor 2 |
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| Synonyms: | Edg5 | S1PR2_RAT | S1pr2 | Sphingosine 1-phosphate receptor 2 (S1P2) |
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| Type: | Protein |
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| Mol. Mass.: | 38749.58 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P47752 |
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| Residue: | 352 |
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| Sequence: | MGGLYSEYLNPEKVQEHYNYTKETLDMQETPSRKVASAFIIILCCAIVVENLLVLIAVAR
NSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGPVTLSLTPLQWFAREGSAFITLSASV
FSLLAIAIERQVAIAKVKLYGSDKSCRMLMLIGASWLISLILGGLPILGWNCLDHLEACS
TVLPLYAKHYVLCVVTIFSVILLAIVALYVRIYFVVRSSHADVAGPQTLALLKTVTIVLG
VFIICWLPAFSILLLDSTCPVRACPVLYKAHYFFAFATLNSLLNPVIYTWRSRDLRREVL
RPLLCWRQGKGATGRRGGNPGHRLLPLRSSSSLERGLHMPTSPTFLEGNTVV
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| BDBM50120514 |
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| n/a |
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| Name | BDBM50120514 |
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| Synonyms: | CHEMBL3618190 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H17BrF4N2O2 |
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| Mol. Mass. | 461.248 |
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| SMILES | OC1(CCN(CC1)C(=O)Nc1cc(F)cc(c1)C(F)(F)F)c1ccc(Br)cc1 |
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| Structure | 
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