| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Pancreatic alpha-amylase |
|---|
| Ligand | BDBM50120838 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1516326 (CHEMBL3618918) |
|---|
| Ki | 1800000±n/a nM |
|---|
| Citation |  Al-Asri, J; Fazekas, E; Lehoczki, G; Perdih, A; Görick, C; Melzig, MF; Gyémánt, G; Wolber, G; Mortier, J From carbohydrates to drug-like fragments: Rational development of novela-amylase inhibitors. Bioorg Med Chem23:6725-32 (2015) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Pancreatic alpha-amylase |
|---|
| Name: | Pancreatic alpha-amylase |
|---|
| Synonyms: | 1,4-alpha-D-glucan glucanohydrolase | AMY2A | AMYP_HUMAN | PA | Pancreatic α-amylase (HPA) | Pancreatic alpha-amylase | Pancreatic alpha-amylase (HPA) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 57709.71 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 511 |
|---|
| Sequence: | MKFFLLLFTIGFCWAQYSPNTQQGRTSIVHLFEWRWVDIALECERYLAPKGFGGVQVSPP
NENVAIYNPFRPWWERYQPVSYKLCTRSGNEDEFRNMVTRCNNVGVRIYVDAVINHMCGN
AVSAGTSSTCGSYFNPGSRDFPAVPYSGWDFNDGKCKTGSGDIENYNDATQVRDCRLTGL
LDLALEKDYVRSKIAEYMNHLIDIGVAGFRLDASKHMWPGDIKAILDKLHNLNSNWFPAG
SKPFIYQEVIDLGGEPIKSSDYFGNGRVTEFKYGAKLGTVIRKWNGEKMSYLKNWGEGWG
FVPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKMAVGFMLAHPYGFTRVMSSYRWP
RQFQNGNDVNDWVGPPNNNGVIKEVTINPDTTCGNDWVCEHRWRQIRNMVIFRNVVDGQP
FTNWYDNGSNQVAFGRGNRGFIVFNNDDWSFSLTLQTGLPAGTYCDVISGDKINGNCTGI
KIYVSDDGKAHFSISNSAEDPFIAIHAESKL
|
|
|
|---|
| BDBM50120838 |
|---|
| n/a |
|---|
| Name | BDBM50120838 |
|---|
| Synonyms: | CHEMBL1233953 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H32N2O15 |
|---|
| Mol. Mass. | 516.4511 |
|---|
| SMILES | OC[C@H]1N\C(=N\O)[C@H](O)[C@@H](O)[C@@H]1O[C@H]1O[C@H](CO)[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
