| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H4 receptor |
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| Ligand | BDBM50006789 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1521725 (CHEMBL3626548) |
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| Ki | 5.3±n/a nM |
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| Citation |  Tichenor, MS; Thurmond, RL; Venable, JD; Savall, BM Functional Profiling of 2-Aminopyrimidine Histamine H4 Receptor Modulators. J Med Chem58:7119-27 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H4 receptor |
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| Name: | Histamine H4 receptor |
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| Synonyms: | HH4R | HRH4_MOUSE | Hrh4 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44272.75 |
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| Organism: | Mus musculus (mouse) |
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| Description: | Cell pellets from SK-N-MC cells transfected with mouse H4 receptor were used in binding assay. |
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| Residue: | 391 |
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| Sequence: | MSESNSTGILPPAAQVPLAFLMSSFAFAIMVGNAVVILAFVVDRNLRHRSNYFFLNLAIS
DFLVGLISIPLYIPHVLFNWNFGSGICMFWLITDYLLCTASVYNIVLISYDRYQSVSNAV
SYRAQHTGIMKIVAQMVAVWILAFLVNGPMILASDSWKNSTNTKDCEPGFVTEWYILTIT
MLLEFLLPVISVAYFNVQIYWSLWKRRALSRCPSHAGFSTTSSSASGHLHRAGVACRTSN
PGLKESAASRHSESPRRKSSILVSLRTHMNSSITAFKVGSFWRSESAALRQREYAELLRG
RKLARSLAILLSAFAICWAPYCLFTIVLSTYPRTERPKSVWYSIAFWLQWFNSFVNPFLY
PLCHRRFQKAFWKILCVTKQPALSQNQSVSS
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| BDBM50006789 |
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| n/a |
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| Name | BDBM50006789 |
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| Synonyms: | CHEMBL3236549 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H19N5 |
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| Mol. Mass. | 221.3021 |
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| SMILES | CC(C)c1cc(nc(N)n1)N1CC[C@@H](N)C1 |r| |
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| Structure | 
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