Ki Summary new BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetIndoleamine 2,3-dioxygenase
LigandBDBM21973
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1523460
Ki 38000±n/a nM
Citation Dounay ABTuttle JBVerhoest PR Challenges and Opportunities in the Discovery of New Therapeutics Targeting the Kynurenine Pathway. J Med Chem 58:8762-82 (2015) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Indoleamine 2,3-dioxygenase
Name:Indoleamine 2,3-dioxygenase
Synonyms:IDO | IDO-1 | INDO | Indoleamine 2,3-Dioxygenasae (IDO) | Indoleamine-pyrrole 2,3-dioxygenase
Type:Enzyme
Mol. Mass.:45330.80
Organism:Homo sapiens (Human)
Description:P14902
Residue:403
Sequence:
MAHAMENSWTISKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVE
KLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLEL
PPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKV
IPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGN
PQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMP
PAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQ
QPKENKTSEDPSKLEAKGTGGTDLMNFLKTVRSTTEKSLLKEG
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM21973
n/a
NameBDBM21973
Synonyms:1-Methyltryptophan, 1 | 2-amino-3-(1-methyl-1H-indol-3-yl)propanoic acid
TypeSmall organic molecule
Emp. Form.C12H14N2O2
Mol. Mass.218.2518
SMILESCn1cc(CC(N)C(O)=O)c2ccccc12
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: