| Reaction Details |
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 | Report a problem with these data |
| Target | Catalase |
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| Ligand | BDBM50127136 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1524705 (CHEMBL3631099) |
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| IC50 | >10000±n/a nM |
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| Citation |  Wu, JS; Lin, SY; Liao, FY; Hsiao, WC; Lee, LC; Peng, YH; Hsieh, CL; Wu, MH; Song, JS; Yueh, A; Chen, CH; Yeh, SH; Liu, CY; Lin, SY; Yeh, TK; Hsu, JT; Shih, C; Ueng, SH; Hung, MS; Wu, SY Identification of Substituted Naphthotriazolediones as Novel Tryptophan 2,3-Dioxygenase (TDO) Inhibitors through Structure-Based Virtual Screening. J Med Chem58:7807-19 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Catalase |
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| Name: | Catalase |
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| Synonyms: | CAT | CATA_HUMAN | Catalase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 59764.51 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_109916 |
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| Residue: | 527 |
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| Sequence: | MADSRDPASDQMQHWKEQRAAQKADVLTTGAGNPVGDKLNVITVGPRGPLLVQDVVFTDE
MAHFDRERIPERVVHAKGAGAFGYFEVTHDITKYSKAKVFEHIGKKTPIAVRFSTVAGES
GSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDPILFPSFIHSQKRNPQTHLKDPD
MVWDFWSLRPESLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQ
GIKNLSVEDAARLSQEDPDYGIRDLFNAIATGKYPSWTFYIQVMTFNQAETFPFNPFDLT
KVWPHKDYPLIPVGKLVLNRNPVNYFAEVEQIAFDPSNMPPGIEASPDKMLQGRLFAYPD
THRHRLGPNYLHIPVNCPYRARVANYQRDGPMCMQDNQGGAPNYYPNSFGAPEQQPSALE
HSIQYSGEVRRFNTANDDNVTQVRAFYVNVLNEEQRKRLCENIAGHLKDAQIFIQKKAVK
NFTEVHPDYGSHIQALLDKYNAEKPKNAIHTFVQSGSHLAAREKANL
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| BDBM50127136 |
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| n/a |
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| Name | BDBM50127136 |
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| Synonyms: | CHEMBL1442185 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H13N3O2 |
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| Mol. Mass. | 303.3147 |
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| SMILES | Cc1ccccc1Cn1nnc2c1C(=O)c1ccccc1C2=O |
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| Structure | 
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