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TargetCatalase
LigandBDBM50127174
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1524705
IC50>10000±n/a nM
Citation Wu JSLin SYLiao FYHsiao WCLee LCPeng YHHsieh CLWu MHSong JSYueh AChen CHYeh SHLiu CYLin SYYeh TKHsu JTShih CUeng SHHung MSWu SY Identification of Substituted Naphthotriazolediones as Novel Tryptophan 2,3-Dioxygenase (TDO) Inhibitors through Structure-Based Virtual Screening. J Med Chem 58:7807-19 (2015) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Catalase
Name:Catalase
Synonyms:CAT | Catalase
Type:PROTEIN
Mol. Mass.:59764.51
Organism:Homo sapiens (Human)
Description:ChEMBL_109916
Residue:527
Sequence:
MADSRDPASDQMQHWKEQRAAQKADVLTTGAGNPVGDKLNVITVGPRGPLLVQDVVFTDE
MAHFDRERIPERVVHAKGAGAFGYFEVTHDITKYSKAKVFEHIGKKTPIAVRFSTVAGES
GSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDPILFPSFIHSQKRNPQTHLKDPD
MVWDFWSLRPESLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQ
GIKNLSVEDAARLSQEDPDYGIRDLFNAIATGKYPSWTFYIQVMTFNQAETFPFNPFDLT
KVWPHKDYPLIPVGKLVLNRNPVNYFAEVEQIAFDPSNMPPGIEASPDKMLQGRLFAYPD
THRHRLGPNYLHIPVNCPYRARVANYQRDGPMCMQDNQGGAPNYYPNSFGAPEQQPSALE
HSIQYSGEVRRFNTANDDNVTQVRAFYVNVLNEEQRKRLCENIAGHLKDAQIFIQKKAVK
NFTEVHPDYGSHIQALLDKYNAEKPKNAIHTFVQSGSHLAAREKANL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50127174
n/a
NameBDBM50127174
Synonyms:CHEMBL3628599
TypeSmall organic molecule
Emp. Form.C23H21N5O3
Mol. Mass.415.4445
SMILESCN1CCN(CC1)C(=O)c1cccc(Cn2nnc3c2C(=O)c2ccccc2C3=O)c1
Structure
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