| Reaction Details |
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 | Report a problem with these data |
| Target | Metallo-beta-lactamase VIM-2 |
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| Ligand | BDBM73278 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1523078 (CHEMBL3631655) |
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| IC50 | 287000±n/a nM |
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| Citation |  Christopeit, T; Carlsen, TJ; Helland, R; Leiros, HK Discovery of Novel Inhibitor Scaffolds against the Metallo-ß-lactamase VIM-2 by Surface Plasmon Resonance (SPR) Based Fragment Screening. J Med Chem58:8671-82 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Metallo-beta-lactamase VIM-2 |
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| Name: | Metallo-beta-lactamase VIM-2 |
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| Synonyms: | Beta-lactamase VIM-2 | Metallo-beta-lactamase VIM-2 (VIM-2) |
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| Type: | Protein |
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| Mol. Mass.: | 28318.00 |
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| Organism: | Pseudomonas aeruginosa (g-Proteobacteria) |
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| Description: | n/a |
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| Residue: | 266 |
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| Sequence: | MFKLLSKLLVYLTASIMAIASPLAFSVDSSGEYPTVSEIPVGEVRLYQIADGVWSHIATQ
SFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRV
GGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHS
TDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGH
GLPGGLDLLKHTTNVVKAHTNRSVVE
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| BDBM73278 |
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| n/a |
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| Name | BDBM73278 |
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| Synonyms: | 4-keto-4-(4-propylphenyl)butyric acid | 4-oxidanylidene-4-(4-propylphenyl)butanoic acid | 4-oxo-4-(4-propylphenyl)butanoic acid | MLS000098355 | SMR000062594 | cid_725542 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H16O3 |
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| Mol. Mass. | 220.2643 |
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| SMILES | CCCc1ccc(cc1)C(=O)CCC(O)=O |
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| Structure | 
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