| Reaction Details |
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 | Report a problem with these data |
| Target | Metallo-beta-lactamase VIM-2 |
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| Ligand | BDBM21642 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1523075 (CHEMBL3631652) |
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| KOFF | 0.025000 s-1 |
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| Citation |  Christopeit, T; Carlsen, TJ; Helland, R; Leiros, HK Discovery of Novel Inhibitor Scaffolds against the Metallo-ß-lactamase VIM-2 by Surface Plasmon Resonance (SPR) Based Fragment Screening. J Med Chem58:8671-82 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Metallo-beta-lactamase VIM-2 |
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| Name: | Metallo-beta-lactamase VIM-2 |
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| Synonyms: | Beta-lactamase VIM-2 | Metallo-beta-lactamase VIM-2 (VIM-2) |
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| Type: | Protein |
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| Mol. Mass.: | 28318.00 |
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| Organism: | Pseudomonas aeruginosa (g-Proteobacteria) |
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| Description: | n/a |
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| Residue: | 266 |
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| Sequence: | MFKLLSKLLVYLTASIMAIASPLAFSVDSSGEYPTVSEIPVGEVRLYQIADGVWSHIATQ
SFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRV
GGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHS
TDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGH
GLPGGLDLLKHTTNVVKAHTNRSVVE
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|
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| BDBM21642 |
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| n/a |
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| Name | BDBM21642 |
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| Synonyms: | (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid | CHEMBL1560 | Capozide | Captopril | Lopirin | SQ 14,225 | SQ14534 | US11491146, Compound L-Captopril |
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| Type | Small organic molecule |
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| Emp. Form. | C9H15NO3S |
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| Mol. Mass. | 217.285 |
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| SMILES | C[C@H](CS)C(=O)N1CCC[C@H]1C(O)=O |
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| Structure | 
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