Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetMu-type opioid receptor
LigandBDBM50130754
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1525033 (CHEMBL3637631)
Ki 343±n/a nM
Citation Molenveld, PBouzanne des Mazery, RSterk, GJStorcken, RPAutar, Rvan Oss, Bvan der Haas, RNFröhlich, RSchepmann, DWünsch, BSoeberdt, M Conformationally restricted¿-opioid receptor agonists: Synthesis and pharmacological evaluation of diastereoisomeric and enantiomeric decahydroquinoxalines. Bioorg Med Chem Lett25:5326-30 (2015) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Mu-type opioid receptor
Name:Mu-type opioid receptor
Synonyms:M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:Enzyme Catalytic Domain
Mol. Mass.:11165.58
Organism:GUINEA PIG
Description:P97266
Residue:98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSI
FTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50130754
n/a
NameBDBM50130754
Synonyms:CHEMBL3634397
TypeSmall organic molecule
Emp. Form.C22H29Cl2N3O3
Mol. Mass.454.39
SMILES[H][C@]12CCC[C@H](N3CCCC3)[C@]1([H])N(CCN2C(=O)OC)C(=O)Cc1ccc(Cl)c(Cl)c1 |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: