| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carbonic anhydrase 14 |
|---|
| Ligand | BDBM50131678 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1523560 (CHEMBL3631208) |
|---|
| Ki | 750±n/a nM |
|---|
| Citation |  Maresca, A; Akyuz, G; Osman, SM; AlOthman, Z; Supuran, CT Inhibition of mammalian carbonic anhydrase isoforms I-XIV with a series of phenolic acid esters. Bioorg Med Chem23:7181-8 (2015) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Carbonic anhydrase 14 |
|---|
| Name: | Carbonic anhydrase 14 |
|---|
| Synonyms: | CA-XIV | CA14 | CAH14_HUMAN | Carbonate dehydratase XIV | Carbonic Anhydrase XIV | Carbonic anhydrase | Carbonic anhydrase 14 | Carbonic anhydrase 14 (CA XIV) | Carbonic anhydrase XIV (CA XIV) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 37665.67 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Human (cloned) isozyme. |
|---|
| Residue: | 337 |
|---|
| Sequence: | MLFSALLLEVIWILAADGGQHWTYEGPHGQDHWPASYPECGNNAQSPIDIQTDSVTFDPD
LPALQPHGYDQPGTEPLDLHNNGHTVQLSLPSTLYLGGLPRKYVAAQLHLHWGQKGSPGG
SEHQINSEATFAELHIVHYDSDSYDSLSEAAERPQGLAVLGILIEVGETKNIAYEHILSH
LHEVRHKDQKTSVPPFNLRELLPKQLGQYFRYNGSLTTPPCYQSVLWTVFYRRSQISMEQ
LEKLQGTLFSTEEEPSKLLVQNYRALQPLNQRMVFASFIQAGSSYTTGEMLSLGVGILVG
CLCLLLAVYFIARKIRKKRLENRKSVVFTSAQATTEA
|
|
|
|---|
| BDBM50131678 |
|---|
| n/a |
|---|
| Name | BDBM50131678 |
|---|
| Synonyms: | CHEMBL3628210 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H18O5 |
|---|
| Mol. Mass. | 314.3325 |
|---|
| SMILES | COc1cc(\C=C\C(=O)OCCc2cccc(O)c2)ccc1O |
|---|
| Structure | 
|
|---|
Search and Browse
