| Reaction Details |
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 | Report a problem with these data |
| Target | Kynurenine 3-monooxygenase |
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| Ligand | BDBM50131813 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1526206 (CHEMBL3636891) |
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| IC50 | 4.0±n/a nM |
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| Citation |  Abdel-Magid, AF Kynurenine Monooxygenase (KMO) Inhibitors for the Treatment of Acute Pancreatitis and Neurodegenerative Disorders. ACS Med Chem Lett6:954-5 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Kynurenine 3-monooxygenase |
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| Name: | Kynurenine 3-monooxygenase |
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| Synonyms: | KMO | KMO_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 55831.03 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1487479 |
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| Residue: | 486 |
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| Sequence: | MDSSVIQRKKVAVIGGGLVGSLQACFLAKRNFQIDVYEAREDTRVATFTRGRSINLALSH
RGRQALKAVGLEDQIVSQGIPMRARMIHSLSGKKSAIPYGTKSQYILSVSRENLNKDLLT
AAEKYPNVKMHFNHRLLKCNPEEGMITVLGSDKVPKDVTCDLIVGCDGAYSTVRSHLMKK
PRFDYSQQYIPHGYMELTIPPKNGDYAMEPNYLHIWPRNTFMMIALPNMNKSFTCTLFMP
FEEFEKLLTSNDVVDFFQKYFPDAIPLIGEKLLVQDFFLLPAQPMISVKCSSFHFKSHCV
LLGDAAHAIVPFFGQGMNAGFEDCLVFDELMDKFSNDLSLCLPVFSRLRIPDDHAISDLS
MYNYIEMRAHVNSSWFIFQKNMERFLHAIMPSTFIPLYTMVTFSRIRYHEAVQRWHWQKK
VINKGLFFLGSLIAISSTYLLIHYMSPRSFLRLRRPWNWIAHFRNTTCFPAKAVDSLEQI
SNLISR
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| BDBM50131813 |
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| n/a |
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| Name | BDBM50131813 |
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| Synonyms: | CHEMBL3634599 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H15ClN2O5 |
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| Mol. Mass. | 362.764 |
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| SMILES | CC(Oc1cc2oc(=O)n(CCC(O)=O)c2cc1Cl)c1ccccn1 |
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| Structure | 
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