| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
|---|
| Ligand | BDBM50133484 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1525967 (CHEMBL3635791) |
|---|
| IC50 | 5400±n/a nM |
|---|
| Citation |  Nakagawa, H; Seike, S; Sugimoto, M; Ieda, N; Kawaguchi, M; Suzuki, T; Miyata, N Peptidyl prolyl isomerase Pin1-inhibitory activity of D-glutamic and D-aspartic acid derivatives bearing a cyclic aliphatic amine moiety. Bioorg Med Chem Lett25:5619-24 (2015) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
|---|
| Name: | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
|---|
| Synonyms: | PIN1 | PIN1_HUMAN | PPIase Pin1 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 18248.11 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1502595 |
|---|
| Residue: | 163 |
|---|
| Sequence: | MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHL
LVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARG
DLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE
|
|
|
|---|
| BDBM50133484 |
|---|
| n/a |
|---|
| Name | BDBM50133484 |
|---|
| Synonyms: | CHEMBL3633022 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H21N3O5S |
|---|
| Mol. Mass. | 403.452 |
|---|
| SMILES | OC(=O)[C@@H](CCC(=O)N1CCOCC1)NC(=O)c1csc(n1)-c1ccccc1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
