| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carbonic anhydrase |
|---|
| Ligand | BDBM10879 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1543853 (CHEMBL3749743) |
|---|
| Ki | 695±n/a nM |
|---|
| Citation |  Vullo, D; Bhatt, A; Mahon, BP; McKenna, R; Supuran, CT Sulfonamide inhibition studies of thea-carbonic anhydrase from the gammaproteobacterium Thiomicrospira crunogena XCL-2, TcruCA. Bioorg Med Chem Lett26:401-5 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Carbonic anhydrase |
|---|
| Name: | Carbonic anhydrase |
|---|
| Synonyms: | 4.2.1.1 | Carbonate dehydratase |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 28438.71 |
|---|
| Organism: | Sulfurihydrogenibium sp. (strain YO3AOP1) |
|---|
| Description: | ChEMBL_116696 |
|---|
| Residue: | 246 |
|---|
| Sequence: | MRKILISAVLVLSSISISFAEHEWSYEGEKGPEHWAQLKPEFFWCKLKNQSPINIDKKYK
VKANLPKLNLYYKTAKESEVVNNGHTIQINIKEDNTLNYLGEKYQLKQFHFHTPSEHTIE
KKSYPLEIHFVHKTEDGKILVVGVMAKLGKTNKELDKILNVAPAEEGEKILDKNLNLNNL
IPKDKRYMTYSGSLTTPPCTEGVRWIVLKKPISISKQQLEKLKSVMVNPNNRPVQEINSR
WIIEGF
|
|
|
|---|
| BDBM10879 |
|---|
| n/a |
|---|
| Name | BDBM10879 |
|---|
| Synonyms: | 2-Hydrazinobenzenesulfonamide | 2-hydrazinylbenzene-1-sulfonamide | CHEMBL176495 | aromatic/heteroaromatic sulfonamide 24 | hydrazide deriv. 18 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C6H9N3O2S |
|---|
| Mol. Mass. | 187.22 |
|---|
| SMILES | NNc1ccccc1S(N)(=O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
