| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carbonic anhydrase, alpha family |
|---|
| Ligand | BDBM10882 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1543854 (CHEMBL3749744) |
|---|
| Ki | 4.1±n/a nM |
|---|
| Citation |  Vullo, D; Bhatt, A; Mahon, BP; McKenna, R; Supuran, CT Sulfonamide inhibition studies of thea-carbonic anhydrase from the gammaproteobacterium Thiomicrospira crunogena XCL-2, TcruCA. Bioorg Med Chem Lett26:401-5 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Carbonic anhydrase, alpha family |
|---|
| Name: | Carbonic anhydrase, alpha family |
|---|
| Synonyms: | Carbonic anhydrase, alpha family |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 35831.01 |
|---|
| Organism: | Thiomicrospira crunogena (strain XCL-2) |
|---|
| Description: | ChEMBL_109899 |
|---|
| Residue: | 315 |
|---|
| Sequence: | MKKRFSFIFIFLVALPLYSANNVAAPLIDLGAEAKKQAQKSAATQSAVPEKESATKVAEK
QKEPEEKAKPEPKKPPHWGYFGEEGPQYWGELAPEFSTCKTGKNQSPINLKPQTAVGTTS
LPGFDVYYRETALKLINNGHTLQVNIPLGSYIKINGHRYELLQYHFHTPSEHQRDGFNYP
MEMHLVHKDGDGNLAVIAILFQEGEENETLAKLMSFLPQTLKKQEIHESVKIHPAKFFPA
DKKFYKYSGSLTTPPCSEGVYWMVFKQPIQASVTQLEKMHEYLGSNARPVQRQNARTLLK
SWPDRNRANTVYEFY
|
|
|
|---|
| BDBM10882 |
|---|
| n/a |
|---|
| Name | BDBM10882 |
|---|
| Synonyms: | 6-ethoxy-1,3-benzothiazole-2-sulfonamide | CHEMBL18 | Ethamide | Ethoxazolamide | Ethoxzolamide | Ethoxzolamide (EZA) | Ethoxzolamide, EZM | Sulfonamide, 3 | US10172837, Ethoxyzolamide | sulfonamide 3 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C9H10N2O3S2 |
|---|
| Mol. Mass. | 258.317 |
|---|
| SMILES | CCOc1ccc2nc(sc2c1)S(N)(=O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
