| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase |
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| Ligand | BDBM10870 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1543853 (CHEMBL3749743) |
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| Ki | 5.5±n/a nM |
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| Citation |  Vullo, D; Bhatt, A; Mahon, BP; McKenna, R; Supuran, CT Sulfonamide inhibition studies of thea-carbonic anhydrase from the gammaproteobacterium Thiomicrospira crunogena XCL-2, TcruCA. Bioorg Med Chem Lett26:401-5 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase |
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| Name: | Carbonic anhydrase |
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| Synonyms: | 4.2.1.1 | Carbonate dehydratase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 28438.71 |
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| Organism: | Sulfurihydrogenibium sp. (strain YO3AOP1) |
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| Description: | ChEMBL_116696 |
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| Residue: | 246 |
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| Sequence: | MRKILISAVLVLSSISISFAEHEWSYEGEKGPEHWAQLKPEFFWCKLKNQSPINIDKKYK
VKANLPKLNLYYKTAKESEVVNNGHTIQINIKEDNTLNYLGEKYQLKQFHFHTPSEHTIE
KKSYPLEIHFVHKTEDGKILVVGVMAKLGKTNKELDKILNVAPAEEGEKILDKNLNLNNL
IPKDKRYMTYSGSLTTPPCTEGVRWIVLKKPISISKQQLEKLKSVMVNPNNRPVQEINSR
WIIEGF
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| BDBM10870 |
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| n/a |
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| Name | BDBM10870 |
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| Synonyms: | 2-N-(4-aminobenzene)-1,3,4-thiadiazole-2,5-disulfonamide | Aminobenzolamide 12 | CHEMBL268439 | aminobenzolamide 17a | aminobenzolamide deriv. 43 | aromatic/heteroaromatic sulfonamide 15 |
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| Type | Small organic molecule |
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| Emp. Form. | C8H9N5O4S3 |
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| Mol. Mass. | 335.383 |
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| SMILES | Nc1ccc(cc1)S(=O)(=O)Nc1nnc(s1)S(N)(=O)=O |
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| Structure | 
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