| Reaction Details |
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 | Report a problem with these data |
| Target | Glycylpeptide N-tetradecanoyltransferase 1 |
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| Ligand | BDBM50135487 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1549624 (CHEMBL3756684) |
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| Ki | 270±n/a nM |
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| Citation |  Yu, Z; Brannigan, JA; Rangachari, K; Heal, WP; Wilkinson, AJ; Holder, AA; Leatherbarrow, RJ; Tate, EW Discovery of pyridyl-based inhibitors of Plasmodium falciparum N-myristoyltransferase. Medchemcomm6:1767-1772 (2016) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Glycylpeptide N-tetradecanoyltransferase 1 |
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| Name: | Glycylpeptide N-tetradecanoyltransferase 1 |
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| Synonyms: | Myristoyl-CoA:protein N-myristoyltransferase (Nmt) | N-myristoyltransferase (NMT1) | NMT | NMT1 | NMT1_HUMAN | Peptide N-myristoyltransferase | Peptide N-myristoyltransferase 1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 56814.10 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30419 |
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| Residue: | 496 |
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| Sequence: | MADESETAVKPPAPPLPQMMEGNGNGHEHCSDCENEEDNSYNRGGLSPANDTGAKKKKKK
QKKKKEKGSETDSAQDQPVKMNSLPAERIQEIQKAIELFSVGQGPAKTMEEASKRSYQFW
DTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENY
VEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEK
KMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRS
LNPRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETKDIPVVHQLLTRYLKQF
HLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMNHPTHKSLKAAY
SFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYN
WKCPSMGAEKVGLVLQ
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| BDBM50135487 |
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| n/a |
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| Name | BDBM50135487 |
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| Synonyms: | CHEMBL3753421 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H22N4O3 |
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| Mol. Mass. | 366.4137 |
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| SMILES | COc1cccc(Cc2noc(n2)-c2cccnc2OC2CCNCC2)c1 |
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| Structure | 
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