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TargetSuppressor of tumorigenicity 14 protein homolog
LigandBDBM50032936
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1544368 (CHEMBL3748444)
Ki 10±n/a nM
Citation Kwon, HKim, YPark, KChoi, SASon, SHByun, Y Structure-based design, synthesis, and biological evaluation of Leu-Arg dipeptide analogs as novel hepsin inhibitors. Bioorg Med Chem Lett26:310-4 (2016) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Suppressor of tumorigenicity 14 protein homolog
Name:Suppressor of tumorigenicity 14 protein homolog
Synonyms:Epithin | Prss14 | ST14_MOUSE | Serine protease 14 | St14 | Suppressor of tumorigenicity 14 protein homolog
Type:PROTEIN
Mol. Mass.:94658.46
Organism:Mus musculus
Description:ChEMBL_116697
Residue:855
Sequence:
MGSNRGRKAGGGSQDFGAGLKYNSRLENMNGFEEGVEFLPANNAKKVEKRGPRRWVVLVA
VLFSFLLLSLMAGLLVWHFHYRNVRVQKVFNGHLRITNEIFLDAYENSTSTEFISLASQV
KEALKLLYNEVPVLGPYHKKSAVTAFSEGSVIAYYWSEFSIPPHLAEEVDRAMAVERVVT
LPPRARALKSFVLTSVVAFPIDPRMLQRTQDNSCSFALHAHGAAVTRFTTPGFPNSPYPA
HARCQWVLRGDADSVLSLTFRSFDVAPCDEHGSDLVTVYDSLSPMEPHAVVRLCGTFSPS
YNLTFLSSQNVFLVTLITNTDRRHPGFEATFFQLPKMSSCGGFLSDTQGTFSSPYYPGHY
PPNINCTWNIKVPNNRNVKVRFKLFYLVDPNVPVGSCTKDYVEINGEKYCGERSQFVVSS
NSSKITVHFHSDHSYTDTGFLAEYLSYDSNDPCPGMFMCKTGRCIRKELRCDGWADCPDY
SDERYCRCNATHQFTCKNQFCKPLFWVCDSVNDCGDGSDEEGCSCPAGSFKCSNGKCLPQ
SQKCNGKDNCGDGSDEASCDSVNVVSCTKYTYRCQNGLCLSKGNPECDGKTDCSDGSDEK
NCDCGLRSFTKQARVVGGTNADEGEWPWQVSLHALGQGHLCGASLISPDWLVSAAHCFQD
DKNFKYSDYTMWTAFLGLLDQSKRSASGVQELKLKRIITHPSFNDFTFDYDIALLELEKS
VEYSTVVRPICLPDATHVFPAGKAIWVTGWGHTKEGGTGALILQKGEIRVINQTTCEDLM
PQQITPRMMCVGFLSGGVDSCQGDSGGPLSSAEKDGRMFQAGVVSWGEGCAQRNKPGVYT
RLPVVRDWIKEHTGV
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  Blast E-value cutoff:
BDBM50032936
n/a
NameBDBM50032936
Synonyms:CHEMBL3356589
TypeSmall organic molecule
Emp. Form.C28H48N10O6S
Mol. Mass.652.809
SMILESCC(C)C[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)c1nccs1 |r|
Structure
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