| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Prostaglandin E2 receptor EP1 subtype |
|---|
| Ligand | BDBM50138044 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1549764 (CHEMBL3757320) |
|---|
| Ki | 1332±n/a nM |
|---|
| Citation |  Kinoshita, A; Higashino, M; Aratani, Y; Kakuuchi, A; Matsuya, H; Ohmoto, K Discovery of highly potent dual EP(2) and EP(3) agonists with subtype selectivity. Bioorg Med Chem Lett26:1016-9 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Prostaglandin E2 receptor EP1 subtype |
|---|
| Name: | Prostaglandin E2 receptor EP1 subtype |
|---|
| Synonyms: | PE2R1_HUMAN | PGE receptor, EP1 subtype | PTGER1 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP1 subtype | Prostaglandin E2 receptor EP1 subtype (EP1) | Prostanoid EP1 receptor |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 41834.57 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P34995 |
|---|
| Residue: | 402 |
|---|
| Sequence: | MSPCGPLNLSLAGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLLALALLAQA
AGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFF
GLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLARVGRYE
LQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGLALLRARWRRRSRR
PPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARRARAHDVEMVGQLV
GIMVVSCICWSPMLVLVALAVGGWSSTSLQRPLFLAVRLASWNQILDPWVYILLRQAVLR
QLLRLLPPRAGAKGGPAGLGLTPSAWEASSLRSSRHSGLSHF
|
|
|
|---|
| BDBM50138044 |
|---|
| n/a |
|---|
| Name | BDBM50138044 |
|---|
| Synonyms: | CHEMBL3754197 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H34N2O5S2 |
|---|
| Mol. Mass. | 494.667 |
|---|
| SMILES | O[C@H](\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O)C1(CCC2CCCCC2)CCC1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
