| Reaction Details |
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 | Report a problem with these data |
| Target | Serum paraoxonase/arylesterase 1 |
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| Ligand | BDBM50144738 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1552279 (CHEMBL3761350) |
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| IC50 | 625710±n/a nM |
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| Citation |  Karatas, MO; Uslu, H; Alici, B; Gökçe, B; Gencer, N; Arslan, O; Arslan, NB; Özdemir, N Functionalized imidazolium and benzimidazolium salts as paraoxonase 1 inhibitors: Synthesis, characterization and molecular docking studies. Bioorg Med Chem24:1392-401 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serum paraoxonase/arylesterase 1 |
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| Name: | Serum paraoxonase/arylesterase 1 |
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| Synonyms: | A-esterase 1 | Aromatic esterase 1 | K-45 | PON | PON 1 | PON1 | PON1_HUMAN | Paraoxonase (PON1) | Paraoxonase (hPON1) | Paraoxonase 1 (PON1) | Serum aryldialkylphosphatase 1 | Serum paraoxonase 1 (PON1) |
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| Type: | Enzyme |
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| Mol. Mass.: | 39719.73 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P27169 |
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| Residue: | 355 |
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| Sequence: | MAKLIALTLLGMGLALFRNHQSSYQTRLNALREVQPVELPNCNLVKGIETGSEDLEILPN
GLAFISSGLKYPGIKSFNPNSPGKILLMDLNEEDPTVLELGITGSKFDVSSFNPHGISTF
TDEDNAMYLLVVNHPDAKSTVELFKFQEEEKSLLHLKTIRHKLLPNLNDIVAVGPEHFYG
TNDHYFLDPYLQSWEMYLGLAWSYVVYYSPSEVRVVAEGFDFANGINISPDGKYVYIAEL
LAHKIHVYEKHANWTLTPLKSLDFNTLVDNISVDPETGDLWVGCHPNGMKIFFYDSENPP
ASEVLRIQNILTEEPKVTQVYAENGTVLQGSTVASVYKGKLLIGTVFHKALYCEL
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| BDBM50144738 |
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| n/a |
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| Name | BDBM50144738 |
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| Synonyms: | CHEMBL3758838 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H15ClN4 |
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| Mol. Mass. | 262.738 |
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| SMILES | [Cl-].Cc1n(C)cc[n+]1Cc1nc2ccccc2[nH]1 |
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| Structure | 
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