| Reaction Details |
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 | Report a problem with these data |
| Target | Melatonin receptor type 1A |
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| Ligand | BDBM50139842 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_1553992 |
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| Ki | 0.200000±n/a nM |
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| Citation |  Couhert, A; Delagrange, P; Caignard, DH; Chartier, A; Suzenet, F; Guillaumet, G Synthesis of 2-arylfuro[3,2-b]pyridines: Effect of the C2-aryl group on melatoninergic activity. Eur J Med Chem109:268-75 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melatonin receptor type 1A |
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| Name: | Melatonin receptor type 1A |
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| Synonyms: | MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A |
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| Type: | Enzyme |
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| Mol. Mass.: | 39392.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P48039 |
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| Residue: | 350 |
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| Sequence: | MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRN
AGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITG
IAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFA
QSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM
FVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQ
NFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
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| BDBM50139842 |
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| n/a |
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| Name | BDBM50139842 |
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| Synonyms: | CHEMBL3765401 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H13IN2O3 |
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| Mol. Mass. | 360.1477 |
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| SMILES | COc1ccc2oc(I)c(CCNC(C)=O)c2n1 |
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| Structure | 
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