| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Palmitoleoyl-protein carboxylesterase NOTUM |
|---|
| Ligand | BDBM50144560 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1551505 (CHEMBL3762926) |
|---|
| EC50 | 13±n/a nM |
|---|
| Citation |  Han, Q; Pabba, PK; Barbosa, J; Mabon, R; Healy, JP; Gardyan, MW; Terranova, KM; Brommage, R; Thompson, AY; Schmidt, JM; Wilson, AG; Xu, X; Tarver, JE; Carson, KG 4H-Thieno[3,2-c]chromene based inhibitors of Notum Pectinacetylesterase. Bioorg Med Chem Lett26:1184-7 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Palmitoleoyl-protein carboxylesterase NOTUM |
|---|
| Name: | Palmitoleoyl-protein carboxylesterase NOTUM |
|---|
| Synonyms: | NOTUM_MOUSE | Notum | Palmitoleoyl-protein carboxylesterase NOTUM |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 56587.82 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_116720 |
|---|
| Residue: | 503 |
|---|
| Sequence: | MGGEVRVLLLLGLLHWVGGSEGRKTWRRRGQQPPQPPPPPPLPQRAEVEPGAGQPVESFP
LDFTAVEGNMDSFMAQVKSLAQSLYPCSAQQLNEDLRLHLLLNTSVTCNDGSPAGYYLKE
SKGSRRWLLFLEGGWYCFNRENCDSRYSTMRRLMSSKDWPHTRTGTGILSSQPEENPHWW
NANMVFIPYCSSDVWSGASPKSDKNEYAFMGSLIIQEVVRELLGKGLSGAKVLLLAGSSA
GGTGVLLNVDRVAELLEELGYPSIQVRGLADSGWFLDNKQYRRSDCIDTINCAPTDAIRR
GIRYWSGMVPERCQRQFKEGEEWNCFFGYKVYPTLRCPVFVVQWLFDEAQLTVDNVHLTG
QPVQEGQWLYIQNLGRELRGTLKDVQASFAPACLSHEIIIRSYWTDVQVKGTSLPRALHC
WDRSFHDSHKASKTPMKGCPFHLVDSCPWPHCNPSCPTIRDQFTGQEMNVAQFLMHMGFD
VQTVAQQQGMEPSKLLGMLSNGN
|
|
|
|---|
| BDBM50144560 |
|---|
| n/a |
|---|
| Name | BDBM50144560 |
|---|
| Synonyms: | CHEMBL3759069 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H11NOS |
|---|
| Mol. Mass. | 229.298 |
|---|
| SMILES | NC(=O)c1cc2CCc3ccccc3-c2s1 |
|---|
| Structure | 
|
|---|
Search and Browse
