| Reaction Details |
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 | Report a problem with these data |
| Target | Casein kinase II subunit alpha' |
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| Ligand | BDBM50144654 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1552124 (CHEMBL3760461) |
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| IC50 | 4.6±n/a nM |
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| Citation |  Ohno, H; Minamiguchi, D; Nakamura, S; Shu, K; Okazaki, S; Honda, M; Misu, R; Moriwaki, H; Nakanishi, S; Oishi, S; Kinoshita, T; Nakanishi, I; Fujii, N Structure-activity relationship study of 4-(thiazol-5-yl)benzoic acid derivatives as potent protein kinase CK2 inhibitors. Bioorg Med Chem24:1136-41 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Casein kinase II subunit alpha' |
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| Name: | Casein kinase II subunit alpha' |
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| Synonyms: | CK2A2 | CSK22_HUMAN | CSNK2A2 | Casein kinase II alpha (prime) | Casein kinase II alpha' | Casein kinase II subunit alpha (CK2A2) | Casein kinase II subunit alpha (CSNK2A2) |
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| Type: | Protein |
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| Mol. Mass.: | 41223.82 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 350 |
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| Sequence: | MPGPAAGSRARVYAEVNSLRSREYWDYEAHVPSWGNQDDYQLVRKLGRGKYSEVFEAINI
TNNERVVVKILKPVKKKKIKREVKILENLRGGTNIIKLIDTVKDPVSKTPALVFEYINNT
DFKQLYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLA
EFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDNY
DQLVRIAKVLGTEELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALD
LLDKLLRYDHQQRLTAKEAMEHPYFYPVVKEQSQPCADNAVLSSGLTAAR
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| BDBM50144654 |
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| n/a |
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| Name | BDBM50144654 |
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| Synonyms: | CHEMBL3760043 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H13N3O4S |
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| Mol. Mass. | 355.368 |
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| SMILES | COc1ccc(cc1)C(=O)Nc1ncc(s1)-c1ccc(nc1)C(O)=O |
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| Structure | 
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