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TargetCarbonic anhydrase 1
LigandBDBM10862
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1552240 (CHEMBL3761242)
Ki 8300±n/a nM
Citation Del Prete, SVullo, DDe Luca, VCarginale, VFerraroni, MOsman, SMAlOthman, ZSupuran, CTCapasso, C Sulfonamide inhibition studies of the฿-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae. Bioorg Med Chem24:1115-20 (2016) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Carbonic anhydrase 1
Name:Carbonic anhydrase 1
Synonyms:CA-I | CA1 | CAB | CAH1_HUMAN | Carbonate dehydratase I | Carbonic anhydrase | Carbonic anhydrase 1 (CA I) | Carbonic anhydrase 1 (CA-I) | Carbonic anhydrase 1 (Recombinant CA I) | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase B | Carbonic anhydrase I | Carbonic anhydrase I (CA I) | Carbonic anhydrase I (CA-I) | Carbonic anhydrase I (CAI) | Carbonic anhydrase I (hCA I) | Carbonic anhydrase isoenzyme I (hCA I) | hCA
Type:Enzyme
Mol. Mass.:28873.37
Organism:Homo sapiens (Human)
Description:P00915
Residue:261
Sequence:
MASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEI
INVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELH
VAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNF
DPSTLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAV
PMQHNNRPTQPLKGRTVRASF
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  Blast E-value cutoff:
BDBM10862
n/a
NameBDBM10862
Synonyms:4-Amino-3-fluorobenzenesulfonamide | 4-amino-3-fluorobenzene-1-sulfonamide | CHEMBL6853 | aromatic/heteroaromatic sulfonamide 7 | halogenosulfanilamide deriv. 5b
TypeSmall organic molecule
Emp. Form.C6H7FN2O2S
Mol. Mass.190.195
SMILESNc1ccc(cc1F)S(N)(=O)=O
Structure
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