| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50179280 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1555270 (CHEMBL3768982) |
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| IC50 | 11±n/a nM |
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| Citation |  Abate, C; Riganti, C; Pati, ML; Ghigo, D; Berardi, F; Mavlyutov, T; Guo, LW; Ruoho, A Development of sigma-1 (s1) receptor fluorescent ligands as versatile tools to studys1 receptors. Eur J Med Chem108:577-85 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 25124.85 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q99720 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
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| BDBM50179280 |
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| n/a |
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| Name | BDBM50179280 |
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| Synonyms: | 1-(4-(6-methoxynaphthalen-1-yl)butyl)-4-methylpiperidine | CHEMBL176941 | CHEMBL545278 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H29NO |
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| Mol. Mass. | 311.4611 |
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| SMILES | COc1ccc2c(CCCCN3CCC(C)CC3)cccc2c1 |
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| Structure | 
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