| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 2 |
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| Ligand | BDBM4703 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1553894 (CHEMBL3767548) |
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| Ki | 46±n/a nM |
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| Citation |  Vullo, D; De Luca, V; Del Prete, S; Carginale, V; Scozzafava, A; Osman, SM; AlOthman, Z; Capasso, C; Supuran, CT Sulfonamide inhibition studies of theż-carbonic anhydrase from the Antarctic bacterium Colwellia psychrerythraea. Bioorg Med Chem Lett26:1253-9 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 2 |
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| Name: | Carbonic anhydrase 2 |
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| Synonyms: | CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II) |
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| Type: | Enzyme |
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| Mol. Mass.: | 29250.71 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P00918 |
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| Residue: | 260 |
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| Sequence: | MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL
NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL
VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP
RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM
VDNWRPAQPLKNRQIKASFK
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| BDBM4703 |
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| n/a |
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| Name | BDBM4703 |
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| Synonyms: | 4-carboxybenzenesulfonamide 1 | 4-sulfamoylbenzoic acid | Benzoic Acid deriv. 31 | CHEMBL414 | JMC522226 Compound 22 | JMC523116 Compound 22 | JMC52646 Compound 23 | aromatic/heteroaromatic sulfonamide 23 |
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| Type | Small organic molecule |
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| Emp. Form. | C7H7NO4S |
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| Mol. Mass. | 201.2 |
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| SMILES | NS(=O)(=O)c1ccc(cc1)C(O)=O |
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| Structure | 
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