| Reaction Details |
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 | Report a problem with these data |
| Target | Glycylpeptide N-tetradecanoyltransferase 1 |
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| Ligand | BDBM50148265 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1556710 (CHEMBL3773953) |
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| Ki | 260±n/a nM |
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| Citation |  Rackham, MD; Yu, Z; Brannigan, JA; Heal, WP; Paape, D; Barker, KV; Wilkinson, AJ; Smith, DF; Leatherbarrow, RJ; Tate, EW Discovery of high affinity inhibitors of Leishmania donovani N-myristoyltransferase. Medchemcomm6:1761-1766 (2016) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Glycylpeptide N-tetradecanoyltransferase 1 |
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| Name: | Glycylpeptide N-tetradecanoyltransferase 1 |
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| Synonyms: | Myristoyl-CoA:protein N-myristoyltransferase (Nmt) | N-myristoyltransferase (NMT1) | NMT | NMT1 | NMT1_HUMAN | Peptide N-myristoyltransferase | Peptide N-myristoyltransferase 1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 56814.10 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30419 |
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| Residue: | 496 |
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| Sequence: | MADESETAVKPPAPPLPQMMEGNGNGHEHCSDCENEEDNSYNRGGLSPANDTGAKKKKKK
QKKKKEKGSETDSAQDQPVKMNSLPAERIQEIQKAIELFSVGQGPAKTMEEASKRSYQFW
DTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENY
VEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEK
KMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRS
LNPRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETKDIPVVHQLLTRYLKQF
HLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMNHPTHKSLKAAY
SFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYN
WKCPSMGAEKVGLVLQ
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| BDBM50148265 |
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| n/a |
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| Name | BDBM50148265 |
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| Synonyms: | CHEMBL3770815 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H22BrN3O3 |
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| Mol. Mass. | 444.322 |
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| SMILES | COc1cccc(Cc2noc(n2)-c2ccc(Br)cc2OC2CCNCC2)c1 |
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| Structure | 
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