| Reaction Details |
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 | Report a problem with these data |
| Target | Kallikrein-5 [D153N] |
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| Ligand | BDBM50292533 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1558621 (CHEMBL3774274) |
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| IC50 | 12500±n/a nM |
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| Citation |  Santos, JA; Kondo, MY; Freitas, RF; dos Santos, MH; Ramalho, TC; Assis, DM; Juliano, L; Juliano, MA; Puzer, L The natural flavone fukugetin as a mixed-type inhibitor for human tissue kallikreins. Bioorg Med Chem Lett26:1485-9 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Kallikrein-5 [D153N] |
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| Name: | Kallikrein-5 [D153N] |
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| Synonyms: | KLK-L2 | KLK5 | KLK5_HUMAN | Kallikrein 5 | Kallikrein-5 | Kallikrein-like protein 2 | SCTE | Stratum corneum tryptic enzyme |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32031.75 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1282456 |
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| Residue: | 293 |
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| Sequence: | MATARPPWMWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARS
DDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGH
YSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNNLMLIKLNRRIRPTKDVRPINVSSHCPS
AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDS
CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS
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| BDBM50292533 |
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| n/a |
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| Name | BDBM50292533 |
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| Synonyms: | CHEMBL446790 | Fukugetin |
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| Type | Small organic molecule |
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| Emp. Form. | C30H22O11 |
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| Mol. Mass. | 558.4891 |
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| SMILES | Oc1ccc(cc1)[C@@H]1Oc2cc(O)cc(O)c2C(=O)[C@H]1c1c(O)cc(O)c2C(=O)CC(Oc12)c1ccc(O)c(O)c1 |r| |
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| Structure | 
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