| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Kallikrein-2 |
|---|
| Ligand | BDBM50292533 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1558641 (CHEMBL3771518) |
|---|
| Ki | 1600±n/a nM |
|---|
| Citation |  Santos, JA; Kondo, MY; Freitas, RF; dos Santos, MH; Ramalho, TC; Assis, DM; Juliano, L; Juliano, MA; Puzer, L The natural flavone fukugetin as a mixed-type inhibitor for human tissue kallikreins. Bioorg Med Chem Lett26:1485-9 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Kallikrein-2 |
|---|
| Name: | Kallikrein-2 |
|---|
| Synonyms: | Glandular kallikrein-1 | KLK2 | KLK2_HUMAN | Kallikrein 2 | Kallikrein-2 | Tissue kallikrein-2 | hGK-1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 28673.68 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_862797 |
|---|
| Residue: | 261 |
|---|
| Sequence: | MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV
LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD
LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS
NDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKP
AVYTKVVHYRKWIKDTIAANP
|
|
|
|---|
| BDBM50292533 |
|---|
| n/a |
|---|
| Name | BDBM50292533 |
|---|
| Synonyms: | CHEMBL446790 | Fukugetin |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C30H22O11 |
|---|
| Mol. Mass. | 558.4891 |
|---|
| SMILES | Oc1ccc(cc1)[C@@H]1Oc2cc(O)cc(O)c2C(=O)[C@H]1c1c(O)cc(O)c2C(=O)CC(Oc12)c1ccc(O)c(O)c1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
