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TargetSigma non-opioid intracellular receptor 1
LigandBDBM50151254
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1559078
Ki 1.1±n/a nM
Citation Franchini SBattisti UMPrandi ATait ABorsari CCichero EFossa PCilia APrezzavento ORonsisvalle SAricÚ GParenti CBrasili L Scouting new sigma receptor ligands: Synthesis, pharmacological evaluation and molecular modeling of 1,3-dioxolane-based structures and derivatives. Eur J Med Chem 112:1-19 (2016) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Sigma non-opioid intracellular receptor 1
Name:Sigma-1 receptor
Synonyms:OPRS1 | SIGMAR1 | Sigma 1-type opioid receptor | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein
Type:Protein
Mol. Mass.:25307.17
Organism:Cavia porcellus (Guinea pig)
Description:Q60492
Residue:223
Sequence:
MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
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  Blast E-value cutoff:
BDBM50151254
n/a
NameBDBM50151254
Synonyms:CHEMBL3769895
TypeSmall organic molecule
Emp. Form.C27H36N2O2
Mol. Mass.420.5869
SMILESC([C@H]1CO[C@](O1)(C1CCCCC1)c1ccccc1)N1CCN(Cc2ccccc2)CC1 |r|
Structure
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