| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50151258 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1559078 (CHEMBL3773934) |
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| Ki | 1.7±n/a nM |
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| Citation |  Franchini, S; Battisti, UM; Prandi, A; Tait, A; Borsari, C; Cichero, E; Fossa, P; Cilia, A; Prezzavento, O; Ronsisvalle, S; Aricò, G; Parenti, C; Brasili, L Scouting new sigma receptor ligands: Synthesis, pharmacological evaluation and molecular modeling of 1,3-dioxolane-based structures and derivatives. Eur J Med Chem112:1-19 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein |
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| Type: | Protein |
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| Mol. Mass.: | 25307.17 |
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| Organism: | Cavia porcellus (Guinea pig) |
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| Description: | Q60492 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
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| BDBM50151258 |
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| n/a |
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| Name | BDBM50151258 |
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| Synonyms: | CHEMBL3770485 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H30N2O2 |
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| Mol. Mass. | 414.5393 |
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| SMILES | C(C1COC(O1)(c1ccccc1)c1ccccc1)N1CCN(Cc2ccccc2)CC1 |
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| Structure | 
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