| Reaction Details |
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 | Report a problem with these data |
| Target | Histone deacetylase 7 |
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| Ligand | BDBM50151375 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1560791 (CHEMBL3778488) |
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| IC50 | >10000±n/a nM |
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| Citation |  Yang, Z; Wang, T; Wang, F; Niu, T; Liu, Z; Chen, X; Long, C; Tang, M; Cao, D; Wang, X; Xiang, W; Yi, Y; Ma, L; You, J; Chen, L Discovery of Selective Histone Deacetylase 6 Inhibitors Using the Quinazoline as the Cap for the Treatment of Cancer. J Med Chem59:1455-70 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone deacetylase 7 |
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| Name: | Histone deacetylase 7 |
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| Synonyms: | HD7 | HDAC7 | HDAC7A | HDAC7_HUMAN | Histone acetylase 7 (HDAC7) | Histone deacetylase 7A | Human HDAC7 |
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| Type: | Chromatin regulator; hydrolase; repressor |
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| Mol. Mass.: | 102942.62 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q8WUI4 |
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| Residue: | 952 |
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| Sequence: | MDLRVGQRPPVEPPPEPTLLALQRPQRLHHHLFLAGLQQQRSVEPMRLSMDTPMPELQVG
PQEQELRQLLHKDKSKRSAVASSVVKQKLAEVILKKQQAALERTVHPNSPGIPYRTLEPL
ETEGATRSMLSSFLPPVPSLPSDPPEHFPLRKTVSEPNLKLRYKPKKSLERRKNPLLRKE
SAPPSLRRRPAETLGDSSPSSSSTPASGCSSPNDSEHGPNPILGSEALLGQRLRLQETSV
APFALPTVSLLPAITLGLPAPARADSDRRTHPTLGPRGPILGSPHTPLFLPHGLEPEAGG
TLPSRLQPILLLDPSGSHAPLLTVPGLGPLPFHFAQSLMTTERLSGSGLHWPLSRTRSEP
LPPSATAPPPPGPMQPRLEQLKTHVQVIKRSAKPSEKPRLRQIPSAEDLETDGGGPGQVV
DDGLEHRELGHGQPEARGPAPLQQHPQVLLWEQQRLAGRLPRGSTGDTVLLPLAQGGHRP
LSRAQSSPAAPASLSAPEPASQARVLSSSETPARTLPFTTGLIYDSVMLKHQCSCGDNSR
HPEHAGRIQSIWSRLQERGLRSQCECLRGRKASLEELQSVHSERHVLLYGTNPLSRLKLD
NGKLAGLLAQRMFVMLPCGGVGVDTDTIWNELHSSNAARWAAGSVTDLAFKVASRELKNG
FAVVRPPGHHADHSTAMGFCFFNSVAIACRQLQQQSKASKILIVDWDVHHGNGTQQTFYQ
DPSVLYISLHRHDDGNFFPGSGAVDEVGAGSGEGFNVNVAWAGGLDPPMGDPEYLAAFRI
VVMPIAREFSPDLVLVSAGFDAAEGHPAPLGGYHVSAKCFGYMTQQLMNLAGGAVVLALE
GGHDLTAICDASEACVAALLGNRVDPLSEEGWKQKPNLNAIRSLEAVIRVHSKYWGCMQR
LASCPDSWVPRVPGADKEEVEAVTALASLSVGILAEDRPSEQLVEEEEPMNL
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| BDBM50151375 |
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| n/a |
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| Name | BDBM50151375 |
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| Synonyms: | CHEMBL3774414 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H24N4O4 |
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| Mol. Mass. | 396.4397 |
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| SMILES | COc1ccc(cc1OCCCC(=O)NO)N(C)c1nc(C)nc2ccccc12 |
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| Structure | 
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