| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier family 2, facilitated glucose transporter member 2 |
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| Ligand | BDBM50155678 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1565337 (CHEMBL3782731) |
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| IC50 | 8700±n/a nM |
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| Citation |  Siebeneicher, H; Bauser, M; Buchmann, B; Heisler, I; Müller, T; Neuhaus, R; Rehwinkel, H; Telser, J; Zorn, L Identification of novel GLUT inhibitors. Bioorg Med Chem Lett26:1732-7 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier family 2, facilitated glucose transporter member 2 |
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| Name: | Solute carrier family 2, facilitated glucose transporter member 2 |
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| Synonyms: | GLUT2 | GTR2_HUMAN | SLC2A2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 57494.38 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_599700 |
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| Residue: | 524 |
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| Sequence: | MTEDKVTGTLVFTVITAVLGSFQFGYDIGVINAPQQVIISHYRHVLGVPLDDRKAINNYV
INSTDELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLGD
TLGRIKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIA
PTALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCP
ESPRYLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSSY
RQPILVALMLHVAQQFSGINGIFYYSTSIFQTAGISKPVYATIGVGAVNMVFTAVSVFLV
EKAGRRSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPW
FMVAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLFT
FFKVPETKGKSFEEIAAEFQKKSGSAHRPKAAVEMKFLGATETV
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| BDBM50155678 |
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| n/a |
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| Name | BDBM50155678 |
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| Synonyms: | CHEMBL3780534 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H22N6O |
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| Mol. Mass. | 386.4497 |
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| SMILES | COc1ccc(cc1)N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1 |
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| Structure | 
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