| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier family 2, facilitated glucose transporter member 3 |
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| Ligand | BDBM50155679 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1565338 (CHEMBL3782732) |
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| IC50 | 170±n/a nM |
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| Citation |  Siebeneicher, H; Bauser, M; Buchmann, B; Heisler, I; Müller, T; Neuhaus, R; Rehwinkel, H; Telser, J; Zorn, L Identification of novel GLUT inhibitors. Bioorg Med Chem Lett26:1732-7 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier family 2, facilitated glucose transporter member 3 |
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| Name: | Solute carrier family 2, facilitated glucose transporter member 3 |
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| Synonyms: | GLUT-3 | GLUT3 | GTR3_HUMAN | Glucose transporter type 3, brain | SLC2A3 | Solute carrier family 2, facilitated glucose transporter member 3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53925.15 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_101113 |
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| Residue: | 496 |
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| Sequence: | MGTQKVTPALIFAITVATIGSFQFGYNTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLT
SLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEML
ILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGS
EELWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQ
EMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAG
VQEPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYN
GMSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLF
PSAAHYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQAHGADRSGKDGV
MEMNSIEPAKETTTNV
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| BDBM50155679 |
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| n/a |
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| Name | BDBM50155679 |
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| Synonyms: | CHEMBL3780772 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H24N6O2 |
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| Mol. Mass. | 416.4757 |
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| SMILES | COc1cccc(c1)-n1ncc2c(ncnc12)N1CCN(CC1)c1ccccc1OC |
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| Structure | 
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