| Reaction Details |
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 | Report a problem with these data |
| Target | D(1A) dopamine receptor |
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| Ligand | BDBM50152845 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1563479 (CHEMBL3783164) |
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| Ki | 11±n/a nM |
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| Citation |  Gadhiya, S; Madapa, S; Kurtzman, T; Alberts, IL; Ramsey, S; Pillarsetty, NK; Kalidindi, T; Harding, WW Tetrahydroprotoberberine alkaloids with dopamine ands receptor affinity. Bioorg Med Chem24:2060-71 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(1A) dopamine receptor |
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| Name: | D(1A) dopamine receptor |
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| Synonyms: | DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A |
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| Type: | Enzyme |
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| Mol. Mass.: | 49303.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21728 |
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| Residue: | 446 |
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| Sequence: | MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTN
FFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVD
RYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLA
ETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKN
CQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGS
GETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIET
VSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPAL
SVILDYDTDVSLEKIQPITQNGQHPT
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| BDBM50152845 |
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| n/a |
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| Name | BDBM50152845 |
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| Synonyms: | CHEMBL3781840 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H29NO4 |
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| Mol. Mass. | 383.4807 |
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| SMILES | CCCCOc1ccc2CC3N(CCc4cc(OC)c(O)cc34)Cc2c1OC |
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| Structure | 
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